Baker Bros. Advisors

Baker Bros. Advisors as of June 30, 2022

Portfolio Holdings for Baker Bros. Advisors

Baker Bros. Advisors holds 117 positions in its portfolio as reported in the June 2022 quarterly 13F filing

Company (Ticker) Portfolio Weight Valued At Change in Shares Share Count Share Price
Seagen 47.1 $8.3B 47M 176.94
Incyte Corporation (INCY) 15.6 $2.7B 36M 75.97
BeiGene Sponsored Adr (BGNE) 10.7 $1.9B 12M 161.85
BioMarin Pharmaceutical (BMRN) 3.6 $632M 7.6M 82.87
ACADIA Pharmaceuticals (ACAD) 3.4 $591M 42M 14.09
Ascendis Pharma A/S Sponsored Adr (ASND) 2.6 $451M 4.9M 92.96
argenx SE Sponsored Adr (ARGX) 2.4 $424M 1.1M 378.88
BioCryst Pharmaceuticals (BCRX) 0.8 $135M 13M 10.58
Kodiak Sciences (KOD) 0.8 $132M 17M 7.64
Global Blood Therapeutics In 0.7 $119M 3.7M 31.95
Abcellera Biologics (ABCL) 0.6 $111M 11M 10.65
Madrigal Pharmaceuticals (MDGL) 0.6 $107M 1.5M 71.58
Mirati Therapeutics 0.5 $95M 1.4M 67.13
Immunocore Holdings Ads (IMCR) 0.5 $94M 2.5M 37.31
Horizon Therapeutics Public SHS 0.5 $92M 1.1M 79.76
Cerus Corporation (CERS) 0.5 $85M 16M 5.29
Travere Therapeutics (TVTX) 0.5 $80M 3.3M 24.23
Replimune Group (REPL) 0.4 $63M 3.6M 17.48
Entrada Therapeutics (TRDA) 0.3 $59M 4.9M 12.18
Igm Biosciences (IGMS) 0.3 $57M 3.2M 18.03
Kymera Therapeutics (KYMR) 0.3 $57M 2.9M 19.69
Krystal Biotech (KRYS) 0.3 $53M 808k 65.66
Prelude Therapeutics (PRLD) 0.3 $53M 10M 5.22
Nurix Therapeutics (NRIX) 0.3 $49M 3.9M 12.67
Legend Biotech Corporation Sponsored Ads (LEGN) 0.3 $47M 857k 55.00
Alkermes SHS (ALKS) 0.3 $45M 1.5M 29.79
Chemocentryx 0.3 $44M 1.8M 24.78
Chinook Therapeutics 0.3 $44M 2.5M 17.49
Insmed Incorporated Com Par $.01 (INSM) 0.2 $43M 2.2M 19.72
Immatics SHS (IMTX) 0.2 $39M 4.4M 8.71
DBV Technologies Sponsored Adr (DBVT) 0.2 $37M 15M 2.55
Sarepta Therapeutics DBCV 1.5% 11/15/2024 (Principal) 0.2 $37M 29M 1.25
Insmed Incorporated Note 0.75% 6/1/2028 (Principal) 0.2 $33M 40M 0.83
Aerovate Therapeutics (AVTE) 0.2 $32M 2.1M 15.63
Amarin Corporation Sponsored Adr (AMRN) 0.2 $32M 21M 1.49
Verastem 0.2 $31M 27M 1.16
Ultragenyx Pharmaceutical (RARE) 0.2 $28M 471k 59.66
2seventy bio Common Stock (TSVT) 0.2 $27M 2.1M 13.20
Kiniksa Pharmaceuticals Com Cl A (KNSA) 0.2 $27M 2.8M 9.69
Biomea Fusion (BMEA) 0.1 $25M 2.1M 11.98
Altimmune (ALT) 0.1 $24M 2.1M 11.70
Invitae (NVTAQ) 0.1 $24M 9.9M 2.44
Pacific Biosciences of California (PACB) 0.1 $24M 5.4M 4.42
Xenon Pharmaceuticals (XENE) 0.1 $23M 752k 30.42
Heron Therapeutics (HRTX) 0.1 $23M 8.1M 2.79
Merus N V (MRUS) 0.1 $23M 995k 22.64
Verve Therapeutics (VERV) 0.1 $22M 1.4M 15.28
Design Therapeutics (DSGN) 0.1 $20M 1.4M 14.00
Affimed Therapeutics B V 0.1 $18M 6.6M 2.77
Instil Bio 0.1 $18M 3.9M 4.62
Otonomy 0.1 $18M 8.4M 2.08
Denali Therapeutics (DNLI) 0.1 $17M 589k 29.43
Rhythm Pharmaceuticals (RYTM) 0.1 $17M 4.1M 4.15
Opthea Sponsored Ads (OPT) 0.1 $17M 2.7M 6.30
Adaptimmune Therapeutics Sponsored Adr (ADAP) 0.1 $17M 9.8M 1.70
Crinetics Pharmaceuticals In (CRNX) 0.1 $15M 828k 18.65
Tricida 0.1 $15M 1.5M 9.68
Forma Therapeutics Holdings SHS 0.1 $14M 2.0M 6.89
Fulgent Genetics (FLGT) 0.1 $11M 201k 54.53
Bluebird Bio (BLUE) 0.1 $10M 2.5M 4.14
Relmada Therapeutics (RLMD) 0.1 $9.4M 495k 18.99
Dice Therapeutics 0.1 $9.1M 588k 15.52
Zymeworks 0.1 $9.1M 1.7M 5.30
Karuna Therapeutics Ord 0.1 $8.9M 70k 126.50
Tscan Therapeutics (TCRX) 0.0 $8.8M 2.8M 3.14
Anaptysbio Inc Common (ANAB) 0.0 $8.7M 427k 20.30
Fibrogen (FGEN) 0.0 $8.6M 816k 10.56
Invitae Corporation Note 2.0% 9/1/2024 (Principal) 0.0 $8.1M 10M 0.79
Cyteir Therapeutics 0.0 $7.9M 2.6M 2.99
Surrozen 0.0 $7.5M 2.5M 3.00
Reata Pharmaceuticals Cl A 0.0 $6.8M 224k 30.39
Achilles Therapeutics Sponsored Ads (ACHL) 0.0 $6.5M 2.6M 2.52
Cymabay Therapeutics 0.0 $6.4M 2.2M 2.95
Atreca Cl A Com (BCEL) 0.0 $6.3M 3.5M 1.79
Talis Biomedical Corp 0.0 $6.2M 7.6M 0.81
Harmony Biosciences Hldgs In (HRMY) 0.0 $6.0M 124k 48.77
Atara Biotherapeutics (ATRA) 0.0 $5.8M 744k 7.79
Vor Biopharma (VOR) 0.0 $5.7M 1.1M 4.97
Centessa Pharmaceuticals Sponsored Ads (CNTA) 0.0 $5.5M 1.1M 4.87
Nkarta (NKTX) 0.0 $4.9M 400k 12.32
Vera Therapeutics Cl A (VERA) 0.0 $4.5M 333k 13.61
Revolution Medicines (RVMD) 0.0 $4.3M 222k 19.49
Edgewise Therapeutics (EWTX) 0.0 $4.0M 500k 7.96
Neoleukin Therapeutics 0.0 $3.9M 3.8M 1.03
Hookipa Pharma Inc equity (HOOK) 0.0 $3.9M 2.4M 1.63
Natera (NTRA) 0.0 $3.5M 100k 35.44
Tango Therapeutics (TNGX) 0.0 $3.4M 750k 4.53
Athira Pharma (ATHA) 0.0 $3.2M 1.0M 3.05
Iteos Therapeutics (ITOS) 0.0 $3.1M 150k 20.60
Evofem Biosciences 0.0 $2.9M 2.6M 1.13
Macrogenics (MGNX) 0.0 $2.6M 893k 2.95
Aligos Therapeutics (ALGS) 0.0 $2.5M 2.1M 1.21
Alector (ALEC) 0.0 $2.4M 239k 10.16
Bioatla (BCAB) 0.0 $2.4M 825k 2.85
Allakos (ALLK) 0.0 $2.2M 703k 3.13
Tcr2 Therapeutics Inc cs 0.0 $2.2M 753k 2.90
Syndax Pharmaceuticals (SNDX) 0.0 $2.1M 111k 19.24
Aeglea Biotherapeutics 0.0 $1.7M 3.4M 0.51
Epizyme 0.0 $1.5M 1.0M 1.47
Akero Therapeutics (AKRO) 0.0 $1.1M 118k 9.45
Atyr Pharma (LIFE) 0.0 $1.1M 374k 2.83
Genetron Holdings Ads 0.0 $774k 455k 1.70
Ngm Biopharmaceuticals (NGM) 0.0 $709k 55k 12.82
Cabaletta Bio (CABA) 0.0 $702k 662k 1.06
Leap Therapeutics 0.0 $644k 560k 1.15
Foghorn Therapeutics (FHTX) 0.0 $612k 45k 13.59
Burning Rock Biotech Sponsored Ads (BNR) 0.0 $609k 209k 2.91
Protara Therapeutics Com Stk (TARA) 0.0 $585k 200k 2.93
Kezar Life Sciences (KZR) 0.0 $512k 62k 8.27
Inozyme Pharma (INZY) 0.0 $510k 107k 4.77
Sera Prognostics Class A Com (SERA) 0.0 $331k 202k 1.64
Vincera Pharma (VINC) 0.0 $319k 241k 1.32
Bellicum Pharmaceuticals 0.0 $296k 249k 1.19
Passage Bio (PASG) 0.0 $276k 117k 2.36
Surrozen W Exp 8/11/2026 (SRZNW) 0.0 $159k 833k 0.19
Logicbio Therapeutics 0.0 $158k 452k 0.35
Neximmune 0.0 $32k 20k 1.60